dna gyrase

Among 41 predicted genes, 6 genes which encode terminase large subunit, including DNA Gyrase B subunit, peptidoglycan binding protein and 3 tail fiber proteins, were functionally known by analysis of bioinformatics.

在41个推定基因中，预测出编码DNA末端酶大亚单位、DNA解旋酶B亚单位、肽聚糖结合蛋白及3个尾丝蛋白等6个基因的功能。

互联网摘选

Antibiotics such as ciprofloxacin can specifically target an essential enzyme called DNA gyrase in bacteria.

像环丙沙星这样的抗生素可以特别的针对细菌中一种基础的叫做DNA促旋酶的酶.

互联网摘选

High level quinolone resistance require mutations in both DNA gyrase gene and topoisomerase ⅳ gene.

高水平的耐药由DNA回旋酶和拓扑异构酶Ⅳ同时发生变异造成。

互联网摘选

It can affect the function of DNA gyrase in bacteria, which results in the inhibition of the duplication and transformation of DNA.

左氧氟沙星可通过作用于细菌的脱氧核糖核酸旋转酶，抑制细菌DNA的复制和转换，发挥广谱抗菌作用。

互联网摘选

The results indicated that the danofloxacin inhibited the DNA gyrase mainly.

表明单诺沙星对DNA旋转酶的抑制是PAE产生的机制之一。

互联网摘选

Inhibitory effect of 5 quinolones on DNA gyrase from Staphylococcus aureus

5种喹诺酮抗菌药对金葡菌DNA螺旋酶的抑制作用

互联网摘选

DNA gyrase is the only topoisomerase that is able to introduce negative supercoils into DNA.

DNA旋转酶是类型Ⅱ拓扑异构酶的一种，也是唯一能够引入负超螺旋的拓扑异构酶。

互联网摘选

OBJECTIVE To study the mutation in DNA gyrase A of Escherichia coli resistante to quinolone antibiotics.

目的研究导致大肠埃希菌DNA回旋酶A亚单位的基因变异耐喹诺酮类药物的机制。

互联网摘选

Objective To study the relation between the alterations in the DNA gyrase subunit A ( GyrA), topoisomerase ⅳ subunit C ( ParC) and fluoroquinolones ( FQNL) resistance in Klebsiella pneumoniae.

目的研究肺炎克雷伯菌DNA旋转酶A亚单位（GyrA）和拓扑异构酶ⅣC亚基（ParC）的变异与其耐氟喹诺酮类（FQNL）的关系。

互联网摘选

DNA gyrase is an essential bacterial topoisomerase that catalyzes the ATP dependent negative supercoiling of double stranded closed circular DNA.

DNA回旋酶是细菌特有的一种拓扑异构酶，它能够利用ATP水解的能量将共价闭合环状DNA转变为负超螺旋DNA，从而维持细菌体内正常的超螺旋水平。

互联网摘选

Objective To study the relationship between the gene mutations of DNA gyrase subunit A ( gyrA) and quinolone resistance in Salmonella typhi.

目的研究伤寒杆菌DNA旋转酶A亚单位基因（gyrA）变异与其耐喹诺酮类的关系。

互联网摘选

The alteration of DNA gyrase and DNA topoisomerase IV is the main mechanism of resistance to fluoroquinolones in E. coli.

DNA促旋酶和拓扑异构酶Ⅳ的改变是大肠埃希菌对氟喹诺酮类耐药的主要机制。

互联网摘选

Fluoroquinolones, primarily by inhibiting bacterial DNA gyrase, so that bacteria can not engage in normal DNA replication and division, resulting in rapid bactericidal effect.

氟喹诺酮类药物主要通过抑制细菌的DNA旋转酶，使细菌不能进行正常DNA复制和分裂，从而产生快速杀菌作用。

互联网摘选